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Wednesday, 26 June 2013

Spectrum for Neostigmine

File:Neostigmine Ion V.1.svg



Neostigmine shows notable UV/VIS absorption at 261nm, 267nm, and 225nm.
Neostigmine's 1H NMR Spectroscopy reveals shifts at: 7.8, 7.7, 7.4, 7.4, 3.8, and 3.1 parts per million. The higher shifts are due to the aromatic hydrogens. The lower shifts at 3.8ppm and 3.1ppm are due to the electronic withdrawing nature of the tertiary and quarterary nitrogen, respectively.



1H spectrum

pnmr of neostigime

13c nmr


HMBC SPECTRUM


IR

Neostigmine, N,N,N-trimethyl-meta-(dimethylcarbomoyloxy)-phenylammonium methylsulfonate, which can be viewed as a simplified analog of physostigmine, is made by reacting 3-dimethylaminophenol with N-dimethylcarbamoyl chloride, which forms the dimethylcarbamate, and its subsequent alkylation using dimethylsulfate forming the desired compound. Neostigmine synthesis.png

Spectral data[

Neostigmine shows notable UV/VIS absorption at 261 nm, 267 nm, and 225 nm.[7]
Neostigmine's 1H NMR Spectroscopy reveals shifts at: 7.8, 7.7, 7.4, 7.4, 3.8, and 3.1 parts per million. The higher shifts are due to the aromatic hydrogens. The lower shifts at 3.8ppm and 3.1ppm are due to the electronic withdrawing nature of the tertiary and quarterary nitrogen, respectively.[8]


  1. Porst H; Kny L (May 1985). "[The structure of degradation products of neostigmine bromide]". Pharmazie. (in German) 40 (5): 325–8. PMID 4034636.
  2. Jump up^ Ferdous, Abu J; Waigh, Roger D (1993). "Application of the WATR technique for water suppression in 1H NMR spectroscopy in determination of the kinetics of hydrolysis of neostigmine bromide in aqueous solution". Journal of Pharmacy and Pharmacology 45 (6): 559–562. doi:10.1111/j.2042-7158.1993.tb05598.xPMID 8103105



Sunday, 23 June 2013

New spectrochemical analysis of naturally aged paper reveals normally unavailable information on the cellulose degradation by-products


How Does Paper Age?

New spectrochemical analysis of naturally aged paper reveals normally unavailable information on the cellulose degradation by-products
Read more

13 C NMR SHIFTS






 


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Khajuraho Group of Monuments is located in India
Khajuraho Group of Monuments
Location of Khajuraho Group of Monuments in India.

Location in Madhya PradeshLocation in Madhya Pradesh

  1. Khajuraho Group of Monuments - Wikipedia, the free ...

    en.wikipedia.org/wiki/Khajuraho_Group_of_Monuments

    The Khajuraho Group of Monuments are a group of Hindu and Jain temples in Madhya Pradesh, India. About 620 kilometres (385 mi) southeast of New Delhi, ...























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13C NMR SPECTRUM OF TOLUENE and OTHERS

C 13 NMR SPECTRUM OF TOLUENE
OTHERS ARE SELF EXPLANATORY

SPECTRUM 2




SPECTRUM 3

 
SPECTRUM 4

 
SPECTRUM5
 
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