DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair, With death on the horizon, nothing will not stop me except God................DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 25Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK GENERICS at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contribution

Saturday 22 November 2014

Stereochemistry of cis/trans Decalins




A useful application of long range couplings for the assignment of ring-fusion stereochemistry in decalin ring system bearing an angular methyl group has been developed (Williamson, K. L.; Howell, T.; Spencer, T. A. J. Am. Chem. Soc. 196688, 325). In the trans-decalins, there are usually several ideal W-pathways for long range coupling between the methyl group and axial protons. In cis-decalins, there are fewer or no such pathways. Thus in a pair of cis/trans isomers, the methyl group in the trans isomer will usually be broader (or will actually show splitting), whereas the cis isomer will have a sharper (unsplit) methyl group.
  

1 comment:

  1. you are clear my mind actually after reading your article i got clear my complete doubt. thanks for such easy understanding post. Sharing on What is the difference between cis and trans isomers? for future aspect at here http://electrotopic.com/what-is-the-difference-between-cis-and-trans-isomers/

    ReplyDelete