DR ANTHONY MELVIN CRASTO,WorldDrugTracker, helping millions, A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair, With death on the horizon, nothing will not stop me except God................DR ANTHONY MELVIN CRASTO Ph.D ( ICT, Mumbai) , INDIA 25Yrs Exp. in the feld of Organic Chemistry,Working for GLENMARK GENERICS at Navi Mumbai, INDIA. Serving chemists around the world. Helping them with websites on Chemistry.Million hits on google, world acclamation from industry, academia, drug authorities for websites, blogs and educational contribution

Tuesday 16 December 2014

Xanifolia- Y and Y1





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 US20130190261

The invention provides a compound comprising the following structure, with the formula of C57H88O23 and the name of 3-O-β-D-galactopyranosyl(1→2)]-α-L-arabinofuranosyl(1→3)-β-D-glucuronopyranosyl-21,22-O-diangeloyl-3β,15α,16α, 21β,22α,28-hexahydroxyolean-12-ene, also known as Xanifolia-Y This compound was isolated from Xanthoceras sorbifolia.



  This invention provides a compound comprising the following structure, with the formula of C65H100O27 and the name of 3-O-[β-D-galactopyranosyl(1→2)]-α-L-arabinofuranosyl(1→3)-β-D-glucuronopyranosyl-21-O-(3,4-diangeloyl)-α-L-rhamnophyranosyl-22-O-acetyl-3β,16α,2β,22α,28-pentahydroxyolean-12-ene, also known as Xanifolia-Y1

The above compounds (Y and Y1) have anti-cancer effect
  FIG. 11 shows the spectrum of proton NMR of Compound Y.

 





FIG. 12 shows 2D NMR (HMQC) results of Compound Y. Also see Table 5.2 for the listed chemical shift data.



FIG. 13 shows 2D NMR (HMBC) results of Compound Y. Also see Table 5.3 for the listed chemical shift data.
 








FIG. 15 shows the Mass spectrum of compound Y with ESI-MS.
 




FIG. 16 shows the Proton NMR spectrum of Compound Y1.
FIG. 17 shows the 2D NMR (HMQC) results of Compound Y1. Also see the chemical shift data from Table 6.2.
 




FIG. 18 shows the 2D NMR (HMBC) results of Y1. Also see the chemical shift data from Table 6.3.
FIG. 19 shows COSY-NMR profile of Y1 with chemical shift data from Table 6.4.

 



 see



 http://www.google.com/patents/US20130190261








 
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