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Monday 26 September 2016

Olmesartan dimer

Figure CN104650046AD00041
olmesartan dimer



Image result for olmesartan dimer impurity






Olmesartan Dimer Ester 


CAS No.
:
1040250-19-8
Molecular Weight
:
874.99
Molecular Formula
:
C48H50N12O5

A dimeric degradation product in stressed tablets of Olmesartan .;Impurity in commercial preparations of Olmesartan 

Synonyms

4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2�-(2H-tetrazol-5-yl)[1,1�-biphenyl]-4-yl]methyl]-1H-imidazoleopyl-1-[[2�-(2H-tetrazol-5-yl) [1,1�-biphenyl]-4-yl]methyl]-1H-imidazol-4-yl]-1-methylethyl Ester; DP-1; 

References

Murakami, T., et al.: J. Pharma. Biomed. Anal., 47, 553 (2008), 






















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