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Rosa Llusar Barelles nace en Almenara (Castellón). En 1983 se licencia en Químicas por la Universidad de Valencia obteniendo el premio extraordinario de licenciatura. Su investigación doctoral se centra en la química de sulfuros de molibdeno y wolframio y se doctora por la Universidad de Valencia en 1987 y por la Universidad de Texas A&M (EE. UU) en 1988 bajo la dirección del profesor F. Albert Cotton. Después de trabajar durante tres años como técnico superior en la sección de investigación y desarrollo de una planta de producción de caprolactama en Castellón, realiza una estancia posdoctoral de un año (1992) con el profesor John D. Corbett en el Ames Laboratory (Iowa State University, EE. UU) investigando nuevas fases sólidas de haluros reducidos de tierras raras. En 1993 accede a una plaza de profesora interina en el Departamento de Ciencias Experimentales de la Universidad Jaume I de Castellón, en 1995 pasa a ser profesora Titular de Química Física y en 2009 Catedrática de Universidad. Desde entonces ha desarrollado su actividad docente en la licenciatura y ahora grado en Química dentro del ámbito de la química física (cuántica, espectroscopia, termodinámica, cinética, electroquímica etc.). Actualmente imparte la asignatura de “nanomateriales” en el máster en Química Aplicada y Farmacológica de la Universitat Jaume I. Ha sido profesora visitante en la Universidad Católica de Valparaíso (Chile), Universidad de Angers (Francia), la Universidad de Rennes (Francia) y en la Universidad Estadual Paulista (Brasil) en 2015.
La Prof. Llusar lidera desde su creación en 1998, el grupo de investigación de materiales moleculares de la Universitat Jaume I (http://www.grupo-rllusar.uji.es/). Su investigación está centrada en la química de clústeres metálicos con especial énfasis en sus propiedades fisicoquímicas de cara al desarrollo de nuevos materiales moleculares multifuncionales con aplicaciones de interés tecnológico en catálisis, electrónica molecular y medicina. Hasta la fecha, la Prof. Llusar ha dirigido diez tesis doctorales, seis de ellas con mención de doctorado europeo o internacional y una sexta realizada en cotutela y defendida en la Universidad Central de Venezuela. Es coautora de más de ciento cincuenta artículos en revistas científicas internacionales indexadas. El Instituto Nikolaev perteneciente a la Academia Rusa de las Ciencias ha reconocido su labor investigadora y de cooperación otorgándole en junio de 2012 el título de Doctora “Honoris Causa”. El Consejo Social de la Universitat Jaume I la galardonó en 2015 con el XVII Premio a la Trayectoria Investigadora.
En el ámbito de la gestión universitaria ha ejercido como vicerrectora de investigación de la Universitat Jaume I desde junio de 2006 durante cuatro años y como directora de los Servicios Centrales de Investigación Científica desde junio de 2010 hasta septiembre de 2014. En la actualidad es miembro del Claustro y del Consejo de Gobierno de la esta Universidad.
Elena Pedrajas Gual is a PhD student in the Molecular Materials Group with a Predoctoral fellowship granted by the University Jaume I in April 2013. Previously, she was licensed in Chemistry in the same university and she studied the Master of Applied and Pharmacologic Chemistry, in the specialty of Advanced Materials. She also was granted with another fellowship by the university and a collaboration fellowship by the Spanish Ministry of Education, which were both developed in the same research group.
She is a member of the Molecular Materials Group since 2012, and her line of research is focused in the synthesis and characterization of M3S4 and M3M'S4clusters (M= Mo, W and M'= transition metal) functionalized with nitrogen donor ligands. Later, the reactivity of the new clusters is studied and also their catalytic activity in industrial processes of interest.
She is the author of an article published in the journal of catalysis ChemCatChem during the year 2015, and she has presented her results in both national and international conferences. She has participated in different research projects of Spanish Ministry, Valencian Community and University Jaume I. She did a temporary stay during two months in the "Leibniz-Institüt für Katalyse" in Rostock (Germany), under the supervision of Professor Matthias Beller.
Her teaching career will start during the academic year 2015-2016 with the course Physical Chemistry IV in the Bachelor's Degree in Chemistry, which consist of an introduction to the basic principles of spectroscopy
Secondary amines are selectively obtained from low value starting materials using hydrogen and a non-noble metal-based catalyst. The reductive amination of aldehydes from nitroarenes or nitroalkanes is efficiently catalyzed by a well-defined diamino molybdenum sulfide cluster in a one-pot homogeneous reaction. The integrity of the molecular cluster catalyst is preserved along the process.
Catal. Sci. Technol., 2017, 7,3008-3016 DOI: 10.1039/C7CY00463J, Paper
Anastasia Rapeyko, Karen S. Arias, Maria J. Climent, Avelino Corma, Sara Iborra Monomers from biomass have been prepared from HMF and methylene active compounds through a one pot process using MIL-100(Fe)/TEMPO/NaNO2 as the catalytic system.
Polymers from biomass: one pot two-step synthesis of furilydenepropanenitrile derivatives with MIL-100(Fe) catalyst
aInstituto de Tecnología Química, Universitat Politècnica de València-Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n, 46022 Valencia, Spain E-mail:email@example.com, firstname.lastname@example.org Fax: (+34) 963877809
Instituto de Tecnologia Quimica UPV-CSIC
Universitat Politècnica de València (UPV)
Valencia Area, Spain
Furilydenepropanenitrile derivatives, which are useful as monomers, have been obtained in high yields by coupling the oxidation of 5-hydroxymethylfurfural (HMF) to 2,5-diformylfuran (DFF) and the Knoevenagel condensation of DFF with methylene active compounds in a one pot process.
The oxidation step was studied using an Fe containing metal–organic framework (MIL-100(Fe), and Fe(BTC)), a Cu containing MOF (Cu3(BTC)2), an Fe exchanged HY zeolite and homogeneous Fe salts in the presence of 2,2,6,6-tetramethylpiperidine-1-oxide (TEMPO) as a cocatalyst, NaNO2 as an additive and oxygen as the terminal oxidant.
The results showed that the synthesized MIL-100(Fe) post treated with NH4F was the most active catalyst achieving 100% HMF conversion with 100% selectivity to DFF and can be reused with good success.
Additionally, the catalytic system has been applied to the oxidation of different primary and secondary alcohols to aldehydes and ketones under mild reaction conditions with good success.
The second step, the Knoevenagel condensation of the obtained DFF with malononitrile or ethyl cyanoacetate, was performed taking advantage of the basicity of the reaction medium.
Atom- and step-economical nucleophilic arylation of azaaromatics via electrochemical oxidative cross C-C coupling reactions
Green Chem., 2017, 19,2931-2935 DOI: 10.1039/C7GC00789B, Communication
O. N. Chupakhin, A. V. Shchepochkin, V. N. Charushin A simple and efficient electrochemical method for the synthesis of asymmetrical bi(het)aryls through direct functionalization of the C(sp2)-H bond in azaaromatics with fragments of (hetero)aromatic nucleophiles has been developed.
aInstitute of Organic Synthesis of the Russian Academy of Sciences, 22 S. Kovalevskoy Street, 620990 Ekaterinburg, Russia E-mail:email@example.com
bUral Federal University, 19 Mira Street, 620002 Ekaterinburg, Russia
The synthesis of asymmetrical bi(het)aryls through direct functionalization of the C(sp2)–H bond in azaaromatics with fragments of (hetero)aromatic nucleophiles has first been carried out under electrochemical oxidative conditions. This versatile method for C–C bond formation between two aryl fragments can be realized under very mild potential-controlled oxidative conditions, and it does require neither incorporation of any halogen atoms or other leaving groups, nor the use of metal catalysts. The use of the electrochemical SHN methodology for modification of azaaromatic compounds has first been demonstrated.
Godfred D. Fianu, Kyle C. Schipper, Robert A. Flowers II Catalytic amounts of titanocene(III) borohydride, generated under mild conditions from commercially available titanocene dichloride, in concert with a stoichiometric hydride source is shown to effectively reduce aldehydes and ketones to their respective alcohols in aprotic media.
aDepartment of Chemistry, Lehigh University, Bethlehem, USA E-mail:firstname.lastname@example.org
Reduction of a wide range of aldehydes and ketones with catalytic amounts of titanocene borohydride in concert with a stoichiometric poly(methylhydrosiloxane) (PMHS) reductant is reported. Preliminary mechanistic studies demonstrate that the reaction is mediated by a reactive titanocene(III) complex, whose oxidation state remains constant throughout the reaction.
Phenyl methanol (2-c) Phenyl methanol (2-c) was prepared from benzaldehyde (1-c) by the procedure outlined in GP1. NMR analysis showed 100% conversion in 1 hour. 86% isolated yield of alcohol product was obtained after complete workup.
In this work the application of green chemistry principles such as process intensification and the replacement of reagents and solvents to more benign alternatives were coupled with the advantages of continuous manufacturing. The reduction of lipophilic aromatic aldehydes using an aqueous alkaline solution of NaBH4 was achieved by means of mechanical shearing and kneading provided by a custom-made batch reactor at the lab scale and a twin screw extruder at the kilo scale. The process was run continuously for 17 min to yield 1.41 kg of product (89% purity). The benefits of running the process in a continuous manner instead a conventional fed-batch mode were discussed in terms of both environmental and economic factors.
Screwing NaBH4 through a Barrel without a Bang: A Kneaded Alternative to Fed-Batch Carbonyl Reductions
Institute of Chemical and Engineering Sciences, 1 Pesek Road, 627833, Jurong Island, Singapore
The chemical industry has been a major part of the Singapore economy for many years, based on a strong foundation as a major oil refining centre with a long history, and strategically placed at the heart of the Asia - Pacific region. In recent years the pharmaceuticals industry has also seen major growth, so that chemistry and chemical engineering science now make a very significant contribution to Singapore's economy.
In order to strengthen this position and to foster future development to grow from dependence solely on manufacturing to secure a more knowledge dependant, high tech research and development based business environment, Agency for Science, Technology and Research (A*STAR) and Economic Development Board (EDB) looked at how to bolster the local science and technology base. As a result, the Institute of Chemical and Engineering Sciences (ICES) came into being, to provide highly trained R&D manpower, to establish a strong science base and to develop technology and infrastructure to support future growth.
Starting from a small centre in the National University of Singapore (NUS), ICES was established as an autonomous national research institute under A*STAR on October 1st 2002. Since that time, we have grown rapidly. We have established world leading laboratories, pilot facilities, and the necessary infrastructure to carry out a world class research programme in chemistry and chemical engineering sciences. We have the capability to cover the range of activities from exploratory research to process development, optimisation and problem solving. We can go from very small lab scale right to kg and pilot scale in one organisation, with all of the necessary skills directly at hand and integrated into a project oriented environment.
Iridium-catalyzed highly efficient chemoselective reduction of aldehydes in water using formic acid as the hydrogen source
Green Chem., 2017, Advance Article DOI: 10.1039/C7GC01289F, Paper
Zhanhui Yang, Zhongpeng Zhu, Renshi Luo, Xiang Qiu, Ji-tian Liu, Jing-Kui Yang, Weiping Tang A highly efficient iridium catalyst is developed for the chemoselective reduction of aldehydes to alcohols in water, using formic acid as a reductant.
bFaculty of Science, Beijing University of Chemical Technology, Beijing, P. R. China
cSchool of Chemistry and Chemical Engineering, University of Chinese Academy of Sciences, Beijing, P. R. China
dSchool of Pharmacy, Gannan Medical University, Ganzhou, P. R. China
eDepartment of Chemistry, University of Wisconsin–Madison, Madison, USA
A water-soluble highly efficient iridium catalyst is developed for the chemoselective reduction of aldehydes to alcohols in water. The reduction uses formic acid as the traceless reducing agent and water as a solvent. It can be carried out in air without the need for inert atmosphere protection. The products can be purified by simple extraction without any column chromatography. The catalyst loading can be as low as 0.005 mol% and the turn-over frequency (TOF) is as high as 73800 mol mol−1 h−1. A wide variety of functional groups, such as electron-rich or deficient (hetero)arenes and alkenes, alkyloxy groups, halogens, phenols, ketones, esters, carboxylic acids, cyano, and nitro groups, are all well tolerated, indicating excellent chemoselectivity.